Showing 1 - 6 of 6
A truly functional Bayesian method for detecting temporally differentially expressed genes between two experimental conditions is presented. The method distinguishes between two biologically different set ups, one in which the two samples are interchangeable, and one in which the second sample...
Persistent link: https://www.econbiz.de/10005117961
Wavelet and Fourier regularization methods are effective for the nonparametric regression problem. We prove that the loss function evaluated for the regularization parameter chosen through GCV or Mallows criteria is asymptotically equivalent in probability to its minimum over the regularization...
Persistent link: https://www.econbiz.de/10005223831
We show that a nonparametric estimator of a regression function, obtained as solution of a specific regularization problem is the best linear unbiased predictor in some nonparametric mixed effect model. Since this estimator is intractable from a numerical point of view, we propose a tight...
Persistent link: https://www.econbiz.de/10005153114
This paper presents a new Bayesian, infinite mixture model based, clustering approach, specifically designed for time-course microarray data. The problem is to group together genes which have “similar” expression profiles, given the set of noisy measurements of their expression levels over a...
Persistent link: https://www.econbiz.de/10010975995
The objective of the present paper is to develop a truly functional Bayesian method specifically designed for time series microarray data. The method allows one to identify differentially expressed genes in a time-course microarray experiment, to rank them and to estimate their expression...
Persistent link: https://www.econbiz.de/10005046597
The paper proposes a method of deconvolution in a periodic setting which combines two important ideas, the fast wavelet and Fourier transform-based estimation procedure of Johnstone "et al". ["J. Roy. Statist. Soc. Ser. B"<b>66</b> (2004) 547] and the multichannel system technique proposed by Casey and...
Persistent link: https://www.econbiz.de/10005324562