Industrial districts are usually referred to as spatially concentrated networks of small and medium-sized firms. These have been seen in Europe and North America, but, so far, have been almost undiscovered in developing countries. Based on the assumption of the strong embedding of the stable and...

This paper considers optimal parametric designs, i.e. designs represented by probability measures determined by a set of parameters, for nonlinear models and illustrates their use in designs for pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/PD) trials. For some practical problems,...

Record linkage databases have been increasingly available and used in pharmacoepidemiology, pharmacoeconomic and outcome studies, where the relationship between drug exposure or intervention and outcome is the main concern. Sometimes the linkage between outcome data and exposure data may be...