<Emphasis Type="Bold">Background: Abacavir sulfate (abacavir) is associated with a hypersensitivity reaction (HSR) that affects 5–8% of patients. While serious complications are rare, failure to identify it, or abacavir re-challenge following HSR, can be fatal. Genetic screening for HLA-B*5701 can identify patients...</emphasis>

Patients with HCV infection indicate a willingness to accept an increased risk of side effects for sufficient improvement in the likelihood of treatment response. </AbstractSection> Copyright Springer International Publishing AG 2012

For many treatments, a patient’s prognosis may be refined by conducting a mid-therapy assessment (MTA). When therapy lasts some time, an MTA predicts a patient’s ultimate outcome based on early signs of response. The availability and timing of such assessments also serve as a mechanism by...

This paper investigates the relationship between income inequality and political party alternation at the US state level using panel data from 1971 to 2015. We hypothesize that income inequality leads to more regime instability in the form of alternation of governors’ parties. We also test the...

Collective ideologies are a feature of the Olympic Games as individual athletes represent entire nations. Prior research has explored one dimension of Olympic ideology, finding a link between national pride and hosting the Olympics. This paper extends the literature by considering a wider...

There is much debate about whether the Medicare Prescription Drug Bill -- the greatest expansion of Medicare benefits since its creation in 1965 -- will improve the health of elderly Americans, and how much it will cost. We model how insurance affects medical care utilization, and subsequently,...

We use a computational linguistic algorithm to measure the topics covered in the text of school teacher contracts in Ohio. We use the topic modeling metrics in a calculation of the concentration of topics covered. This allows us to assess how expansive each contract is. As a proof of concept, we...

The effects of the HIV/AIDS epidemic on fertility in Africa remains ill understood. To align the contrasting findings of recent empirical research, we develop a portfolio model that captures the potential trade-off between "quantity" and "quality" of offspring. According to this theoretical...