Abstract The notion that an independent central bank reduces a country’s inflation is a controversial hypothesis. To date, it has not been possible to satisfactorily answer this question because the complex macroeconomic structure that gives rise to the data has not been adequately...

Scalar-on-function regression problems with continuous outcomes arise naturally in many settings, and a wealth of estimation methods now exist. Despite the clear differences in regression model assumptions, tuning parameter selection, and the incorporation of functional structure, it remains...

Abstract Marginal structural Cox Models (Cox MSMs) have been used to estimate the causal effect of a time-varying treatment on the hazard when there exist time-dependent confounders, which are themselves also affected by previous treatment. A Cox MSM can be estimated via the...

Abstract Marginal Structural Models (MSMs), with the associated method of inverse probability weighting (IPW), have become increasingly popular in epidemiology to model and estimate the joint effects of a sequence of exposures. This popularity is largely related to the relative simplicity of the...

Efficient semiparametric estimation of longitudinal causal effects is often analytically or computationally intractable. We propose a novel restricted estimation approach for increasing efficiency, which can be used with other techniques, is straightforward to implement, and requires no...

In this paper, some new statistical methods are proposed, for making inferences about the parameter indexing a Cox proportional hazards marginal structural model for point exposure. Under the key assumption that unmeasured confounding is absent, we propose a new class of closed-form estimators...

A diabetes diagnosis can motivate its recipients to reduce their health risks by changing lifestyles but can adversely affect their economic activity. We investigate the effect of a diabetes diagnosis on employment status and behavioural risk-factors taking into account their potentially...

We describe analytic approaches for study designs that, like large simple trials, can be better characterized as longitudinal studies with baseline randomization than as either a pure randomized experiment or a purely observational study. We (i) discuss the intention-to-treat effect as an effect...

A diabetes diagnosis can motivate its recipients to reduce their health risks by changing lifestyles but can adversely affect their economic activity. We investigate the effect of a diabetes diagnosis on employment status and behavioural risk-factors taking into account their potentially...

Background: Strokes cause an estimated annual health care burden of 170 billion euros across Europe. Atrial fibrillation is one of the major risk factors for stroke and increases the individual risk 4.2-fold. But prevention with anticoagulants may reduce this risk by 70%. Screening methods are...