A wide range of chemicals are intentionally added to, or unintentionally found in, food products, often in very small amounts. Depending on the situation, the experimental data needed to complete a dietary risk assessment, which is the scientific basis for protecting human health, may not be...

In the regulatory assessment of chemicals, the use of in silico prediction methods such as (quantitative) structure-activity relationship models ([Q]SARs), is increasingly required or encouraged, in order to increase the efficiency and effectiveness of the risk assessment process, and to...

This report presents research results obtained in the framework of a project on the Applicability of Quantitative Structure-Activity Relationship (QSAR) analysis in the evaluation of the toxicological relevance of metabolites and degradates of pesticide active substances. During this project,...

In the regulatory assessment of chemicals, Quantitative Structure-Activity Relationship (QSAR) models are playing an increasingly important role in predicting properties needed for hazard and risk assessment. The JRC QSAR Model Database provides information on the validity of QSAR models that...

To address financial and animal welfare concerns in the regulatory assessment of chemicals, computational (in silico) models are being increasingly used as a means of filling data gaps and contributing to weight of evidence arguments. This Tutorial introduces the JRC QSAR Model Database and...

This is the final report of the Nanocomput project, the main aims of which were to review the current status of computational methods that are potentially useful for predicting the properties of engineered nanomaterials, and to assess their applicability in order to provide advice on the use of...

This is the final report of the Nanocomput project, the main aims of which were to review the current status of computational methods that are potentially useful for predicting the properties of engineered nanomaterials, and to assess their applicability in order to provide advice on the use of...

To address financial and animal welfare concerns in the regulatory assessment of chemicals, computational (in silico) models are being increasingly used as a means of filling data gaps and contributing to weight of evidence arguments. This Tutorial introduces the JRC QSAR Model Database and...