Greenberg, Paul; Corey-Lisle, Patricia K.; Birnbaum, Howard - In: PharmacoEconomics 22 (2004) 6, pp. 363-373
Background: Conservative estimates indicate between 10% and 20% of all individuals with major depressive disorders (MDDs) fail to respond to conventional antidepressant therapies. Amongst those with MDD, individuals with treatment-resistant depression (TRD) have been found to be frequent users...