The sensitivity to the specification of the prior in a hidden Markov model describing homogeneous segments of DNA sequences is considered. An intron from the chimpanzee [alpha]-fetoprotein gene, which plays an important role in embryonic development in mammals, is analysed. Three main aims are...

Modern technology now has the ability to generate large datasets over space and time. Such data typically exhibit high autocorrelations over all dimensions. The field trial data motivating the methods of this paper were collected to examine the behaviour of traditional cropping and to determine...

In this paper, we describe an analysis for data collected on a three-dimensional spatial lattice with treatments applied at the horizontal lattice points. Spatial correlation is accounted for using a conditional autoregressive model. Observations are defined as neighbours only if they are at the...

This document is the aggregation of several discussions of Lopes et al. (2010) we submitted tothe proceedings of the Ninth Valencia Meeting, held in Benidorm, Spain, on June 3–8, 2010, inconjunction with Hedibert Lopes’ talk at this meeting. The main point in those discussions is...

Precise identification of the time when a process has changed enables process engineers to search for a potential special cause more effectively. In this paper, we develop change point estimation methods for a Poisson process in a Bayesian framework. We apply Bayesian hierarchical models to...

Abstract only: Today’s data analysts and modellers are in the luxurious position of being able to more closely describe, estimate, predict and infer about complex systems of interest, thanks to ever more powerful computational methods but also wider ranges of modelling distributions. Mixture...

This paper presents the findings of the most comprehensive program of study to date aimed at quantifying the number, size distribution and evaporation of droplets produced during virtually any expiratory activity. This international research program included teams of investigators from a number...

Background: It remains unclear whether it is possible to develop a spatiotemporal epidemic prediction model for cryptosporidiosis disease. This paper examined the impact of social economic and weather factors on cryptosporidiosis and explored the possibility of developing such a model using...

A Bayesian Markov chain Monte Carlo methodology is developed for the estimation of multivariate linear Gaussian state space models. In particular, an efficient simulation smoothing algorithm is proposed that makes use of the univariate representation of the state space model. Substantial gains...