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Background: Fingolimod is an innovative drug with a significant budget impact in the treatment of MS in Spain. The aim … of this study was to calculate the direct cost comparison of glatiramer acetate and fingolimod for the treatment of … glatiramer acetate and fingolimod, based on a 1-year time horizon. In addition to the pharmacological costs, resource use was …
Persistent link: https://www.econbiz.de/10009755990
Fingolimod therapy requires twice the investment as glatiramer acetate. </AbstractSection> Copyright Sanchez-de la Rosa …
Persistent link: https://www.econbiz.de/10010998799
Objective: The Escala Study evidenced that the administration of glatiramer acetate for relapsing-remitting multiple sclerosis improved the spasticity of patients previously treated with interferon-β. However, whether such an improvement was translated into cost savings remained unclear. We...
Persistent link: https://www.econbiz.de/10011599855
Objective: The Escala Study evidenced that the administration of glatiramer acetate for relapsing-remitting multiple sclerosis improved the spasticity of patients previously treated with interferon-β. However, whether such an improvement was translated into cost savings remained unclear. We...
Persistent link: https://www.econbiz.de/10011472089
Multiple sclerosis (MS) is a chronic neurological disease of adults that affects over 1 million people worldwide. Relapsing-remitting MS, characterized by acute attacks (relapses) followed by complete or partial remissions, is the most common type of MS at disease onset. Over time, most patients...
Persistent link: https://www.econbiz.de/10005590214
Invasive species are one of the main reasons for the loss of biodiversity. Therefore, national strategies are developed to deal with biological invasions. Economic evaluation as a tool of policy advice has to take into account three challenges: (1) reflecting ecological knowledge, which is...
Persistent link: https://www.econbiz.de/10010304537
Aim: To carry out a systematic review of studies that have conducted economic evaluations on smoking relapse prevention interventions by critically appraising the quality of the methodology. Methods: All relevant articles were identified by searching three electronic databases MEDLINE, EMBASE,...
Persistent link: https://www.econbiz.de/10011335884
We introduce a methodology for dynamic modelling and forecasting of realized covariance matrices based on generalization of the heterogeneous autoregressive model (HAR) for realized volatility. Multivariate extensions of popular HAR framework leave substantial information unmodeled in residuals....
Persistent link: https://www.econbiz.de/10011340631
This paper presents a brief literature review concerning the costs and benefits of electric vehicles and hybrid electric vehicles, highlighting their advantages in terms of greenhouse gas emissions reductions. Even though electric and electro-hybrid vehicles must still overcome many cultural and...
Persistent link: https://www.econbiz.de/10011372243
Nach dem Verbot der konventionellen Käfighaltung in Deutschland stellte sich die Frage nach der Wirtschaftlichkeit von artgerechten alternativen Haltungssystemen. Über die Kleingruppenhaltung, welche relativ neu ist und wieder zur Debatte steht, liegen kaum praxisnahe Informationen vor. Diese...
Persistent link: https://www.econbiz.de/10010326559