A hierarchical scheme for cooperativity and folding in proteins

We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first-order phase transition, cooperativity and is exactly solvable. It also shows an unexpected symmetry between folding and unfolding pathways as suggested by a recent experiment.

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Year of publication:	1998
Authors:	Hansen, Alex ; Jensen, Mogens H. ; Sneppen, Kim ; Zocchi, Giovanni
Published in:	Physica A: Statistical Mechanics and its Applications. - Elsevier, ISSN 0378-4371. - Vol. 250.1998, 1, p. 355-361
Publisher:	Elsevier

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Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://www.econbiz.de/10010874648