Bayesian hierarchical regression models for detecting QTLs in plant experiments
Quantitative trait loci (QTL) mapping is a growing field in statistical genetics. In plants, QTL detection experiments often feature replicates or clones within a specific genetic line. In this work, a Bayesian hierarchical regression model is applied to simulated QTL data and to a dataset from the Arabidopsis thaliana plants for locating the QTL mapping associated with cotyledon opening. A conditional model search strategy based on Bayesian model averaging is utilized to reduce the computational burden.
Year of publication: |
2008
|
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Authors: | Boone, Edward ; Simmons, Susan ; Bao, Haikun ; Stapleton, Ann |
Published in: |
Journal of Applied Statistics. - Taylor & Francis Journals, ISSN 0266-4763. - Vol. 35.2008, 7, p. 799-808
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Publisher: |
Taylor & Francis Journals |
Subject: | hierarchical models | Bayesian statistics | quantitative trait loci | Bayesian model averaging | recombinant inbred Lines |
Saved in:
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