Folding kinetics of two-state proteins based on the model of general random walk in native contact number space

We investigated the folding kinetics of a series of two-state proteins by using the model of general random walk in native contact number space, and derive the observed linear relationship between the logarithms of the folding rate constants and the numbers of native contacts from “kinetic viewpoint”. The protein folding speed limit and stability in this model are consistent with experimental observations.

MoreLess

Year of publication:	2010
Authors:	Guo, J.S. ; Mi, D. ; Sun, Y.Q.
Published in:	Physica A: Statistical Mechanics and its Applications. - Elsevier, ISSN 0378-4371. - Vol. 389.2010, 4, p. 761-766
Publisher:	Elsevier
Subject:	Protein folding \| Folding rate \| Native contact \| Folding kinetics \| Random walk model

More details

Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://ebvufind01.dmz1.zbw.eu/10011064221