This special issue collects a selection of the papers presented at the conference-Festschrift in honor of Giancarlo Gandolfo held in Rome on September 20-21, 2010. The conference was organized by Giuseppe De Arcangelis (Sapienza University of Rome), Pier Carlo Padoan (OECD and Sapienza University of Rome), Luca Antonio Ricci (International Monetary Fund) and Enrico Saltari (Sapienza University of Rome) with funding by various departments and institutions of Sapienza University of Rome and by the Bank of Italy. The contributions cover many different areas of economic dynamics and continuous-time disequilibrium macroeconomics, two fields to which Giancarlo Gandolfo has been continuously contributing for the last three decades.