Abstract The selected papers collected in this special issue were presented at the “Interacting agents and nonlinear dynamics in macroeconomics” workshop organized by Marji Lines , Sebastiano Manzan, and Frank Westerhoff which was held at the University of Udine, Udine (Italy), on June 9-11, 2010. The papers represent a wide range of recent approaches that assume heterogeneous agents to explain macroeconomic dynamics.