Investigation on Mechanical, Biocorrosion and Biocompatibility Behaviour of Hap Assisted Sr Based Mg Composites

Numerous biodegradable Mg-based biomaterials have been developed in present years because of their excellent biocompatibility, biodegradation, and mechanical properties. Mg-based composite is a suitable candidate for orthopaedic implants, such as supporting the fractured bone due to its superb biocompatibility and biodegradation properties. In this present work, Mg-based biomaterial is developed by incorporating low wt% of alloying elements like Zn, Ca, Mn, Sr, and ceramic powders HAp to improve biocompatibility, biodegradability and strengthen the mechanical properties. In this study, the Mg-4Zn-3Ca-1HAp-0.5Mn and Mg-4Zn-2.9Ca-1HAp-0.5Mn-0.1Sr composites were prepared, and the mechanical, microstructure, in-vitro degradation behaviour of these composites were studied. The Mg-4Zn-2.9Ca-1HAp-0.5Mn-0.1Sr composite has good mechanical properties (UTS, YS, elongation) and a low uniform in-vitro degradation rate (0.587 mm/year). From the dynamic mechanical analysis (DMA) it was found that the composites have better damping characteristics than the pure Mg. The composites were chosen for further evaluation. All the composite were showing no cytotoxicity to MG63 cells. The composite having Sr with PVA/ZrO2 coating showed the highest cell viability. On the basis of the above observation, the viability of the Mg-Zn-Ca-HAp-Mn and Mg-Zn-Ca-HAp-Mn-Sr composites discussed systematically for the use as orthopaedic implant. This investigation provides a new idea for the evolution of high performance Sr based Mg composite having excellent mechanical and corrosion properties while successfully reducing the cytotoxicity effect