Modelling and simulation of electrically stimulated nerve and muscle fibers: A review

The behaviour of nerve and muscle fibers can be simulated by computers using physiologically established equations. This paper discusses several local models and their applications. Spatial models are necessary for modelling propagating activities of fibers. Spatial models can be obtained by the combination of local models according to an electrical network. The resulting system of differential equations allows simulation of intracellular as well as extracellular stimulated fibers. The problems to be investigated are listed with numerous references.