This paper aimed at enlightening the emergence of multi-stakeholder initiatives in Vietnam that enable individuals, businesses, and civic societies to undertake the complex sustainability issues in the international business environment. Currently, the philosophy of involving multi-stakeholder initiatives groups in Vietnam for resource management seems overwhelming. Equally, the motive for studying a phenomenon like multi-stakeholder dialogue is a novel outlook that did not catch various researchers’ eye earlier. Nowadays, the European multi-stakeholder innovation platform tries to address the European societal challenges and policies due to their roles in the upcoming new program of Horizon 2020. National policy makers using them as building blocks for implementing different strategies such as research and development and regional policies. The approach of multi-stakeholder initiatives in Vietnam is to respond to the limited capacity and resources of individuals, societal sectors, governments, businesses, and civic societies. Thus, this study was conducted to demonstrate the significance of multi-stakeholder initiatives in Vietnam that create a broad multi-stakeholder (science, policy, business, society, including SMEs, public and private investors) and multi-level (local, regional, national, and Europe) innovation platforms to meet a range of societal challenges through Horizon 2020 in order to facilitate the development of committed innovation partnerships and identify how different types of firms, people, and knowledge at national and international levels making civil society organizations, nongovernmental organizations, and individuals and institutions more innovative and competitive. Finally, this paper proposed some recommendations based on assumptions underlying research questions that added value to promote dialogue and collaboration across levels and with key international partners
