Nonparametric estimation of age-at-onset distributions from censored kin-cohort data

We present a nonparametric estimator of genotype-specific age-at-onset distributions from kin-cohort data. Standard error calculations are derived and the methodology is illustrated through an analysis of the influence of mutations of the Parkin gene on Parkinson's disease. Semiparametric efficiency considerations are briefly discussed. Copyright 2007, Oxford University Press.

MoreLess

Year of publication:	2007
Authors:	Wang, Yuanjia ; Clark, Lorraine N. ; Marder, Karen ; Rabinowitz, Daniel
Published in:	Biometrika. - Biometrika Trust, ISSN 0006-3444. - Vol. 94.2007, 2, p. 403-114
Publisher:	Biometrika Trust

More details

Extent:	application/pdf
Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://www.econbiz.de/10005569417