On the stochastic thermodynamics of reactive systems

We develop a theoretical framework for the stochastic thermodynamics of reactive systems. We show that the transition probabilities per unit time of reactive events must satisfy specific constraints, in order for stochastic approaches to lead to physically meaningful results in the macroscopic limit. We discuss how these constraints affect the properties of stochastic fluxes and forces, and entropy production. We also see how they can be used to derive various expressions of fluctuation theorems.