Preparation and Thermogenic Performance of Monodisperse Ferromagnetic Fe/Sio2 Nanoparticles for Magnetic Hyperthermia and Thermal Ablation

Ferromagnetic nanoparticles have great potential to be used in the field of magnetic hyperthermia and thermal ablation due to its high saturation magnetization ( M s ) and high heating efficiency. In this paper, monodisperse spherical α-Fe 2 O 3 nanoparticles were prepared by hydrothermal method using FeCl 3 , NaHCO 3 and Na 2 SO 4 as reactants. Then monodisperse Fe/SiO 2 nanoparticles with core/shell structure were obtained by coating SiO 2 on the surface of α-Fe 2 O 3 nanoparticles and reducing at 500°C in hydrogen atmosphere. The diameter of Fe core is about 230 nm and the thickness of SiO 2 coating is about 75 nm. Magnetic measurements show that Fe/SiO 2 nanoparticles exhibit typical ferromagnetic properties with M s about 132.5 emu/g at 25°C. As-obtained Fe/SiO 2 nanoparticles have higher heating efficiency than superparamagnetic ferrite nanoparticles. The high heating ability is related to the hysteresis loss mechanism during alternating magnetization. The results show that Fe/SiO 2 nanoparticles have potential applications in magnetic hyperthermia and thermal ablation