This Research has the objective of studying the cause of injuries at work of the construction workers of high-rice building. Injury characteristic, severity of the injury, damage caused by the injuries at work of the construction workers, the capability of the high-rise construction workers and to study the correlation between the injuries at work of the construction workers and the capability of the high-rise building construction workers in Thailand. The researcher did the research as a mix research, studied as a qualitative research and quantitative research. Tools used in qualitative research is by recording form of non-participation observation, recording form of participated observation and recording of in-depth interviews. Tools used in the quantitative research are the questionnaires the researcher set up. The researcher collected the information for this research during October 2016-March 2017. It is found from the research that 1) The cause from injuries at work of the construction workers of high-rise buildings consisted of Man, machinery and equipment, environment and safety management 2) Injury characteristic of the construction workers of high-rise buildings are: skin injury, respiratory injury, sight and eye injuries, hearing, muscular injury and skeleton injury 3) The severity of the injuries consisted of death, disabled, loss of organs, dismemberment, more than 3 days leave of absence, less than 3 days leave of absence 4) Damage and loss caused by the injuries of the construction workers of high-rise buildings consisted of: Being charged and prosecuted of the criminal case, having to pay compensation and hospital charges, loss of spirit, dishearten, loss of confident, the work is delayed over the planned schedule. 5) The task demand factors of the construction workers are, work design, task factor, environmental factor, work behavior factor 6) Capability of the construction workers consisted of competency, human factor, attention factors, supervision, monitoring and inspection 7) The injuries of the construction workers have a high level of correlation with the capability of the construction workers of high-rise buildings in Thailand with statistic significant at .01, correlation coefficient at .762
