The topology of the transcription regulatory network in the yeast, Saccharomyces cerevisiae

A central goal of postgenomic biology is the elucidation of the regulatory relationships among all cellular constituents that together comprise the ‘genetic network’ of a cell or microorganism. Experimental manipulation of gene activity coupled with the assessment of perturbed transcriptome (i.e., global mRNA expression) patterns represents one approach toward this goal, and may provide a backbone into which other measurements can be later integrated.

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Year of publication:	2003
Authors:	Farkas, I. ; Jeong, H. ; Vicsek, T. ; Barabási, A.-L. ; Oltvai, Z.N.
Published in:	Physica A: Statistical Mechanics and its Applications. - Elsevier, ISSN 0378-4371. - Vol. 318.2003, 3, p. 601-612
Publisher:	Elsevier
Subject:	Bioinformatics \| mRNA expression \| Analysis of graph topology

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Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://www.econbiz.de/10011057134