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Frailty models are the possible choice to counter the problem of the unobserved heterogeneity in individual risks of … disease and death. Based on earlier studies, shared frailty models can be utilised in the analysis of bivariate data related … to survival times (e.g. matched pairs experiments, twin or family data). In this article, we assume that frailty acts …
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and fourth-order polynomials on the other. Representing heterogeneity by cohort effects is compared with representing … heterogeneity by random and fixed individual effects. On the whole, the age coefficients in the estimated regressions are quite … sensitive to how heterogeneity is modeled. …
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